Research Interests:

 

1.      Synthesis of Polyethylene oxide (PEO) based block copolymers for drug formulations and their applications for efficient delivery of water-insoluble anti-Cancer and anti- Alzheimer drugs to Central Nervous System.

2.      Synthesis of Specially Designed peptides Using Solid Phase Peptide Synthesis (SPPS) Methodology for application in drug development, drug delivery and toxicity reduction of antifungal and antibiotic drugs.

3.      Studies on the toxicity reduction of antifungal and antibiotic drugs like Amphotericin B (AmB), Etoposide etc.

4.      Development of Research Facility for the Production of Composite Polymer Particles and Their Applications in Biomedical Field and Coating.

5.      Development of Stimuli-responsive Composite Polymer Particles and Their Application in the Biomedical Field.

6.      Development of methodology for organic synthesis including natural products of medicinal interest.

7.      Synthesis of N-acylated derivatives of amino-compounds like amino acids and urea and evaluation of their microbial activities.

8.      Synthesis and studies of antibacterial and antifungal activities of oxygenated flavones.

9.      Studies of biochemical changes in drug abusers (e.g., phensedyl-Codeine containing cough syrup-addicts.

10.   Study on the production of micron-sized cyano functionalized polymer particles.

11.  Kinetics of poly (styrene-2-hydroxyethyl methacrylate) copolymerization in emulsion and microemulsion systems.

12.  Nitrogen – its fixation to polymer and release behavior in soil.

13.  Promotional Effect of Metal Polymer Complexes on the Hydrolysis of Amino Acid Esters.

 

List of Research Publications:

 

1.                    Bong K. Yoo, M. A. Jalil Miah, Eung-Seok Lee, Kun Han, “Partially benzylated decapeptide of polyaspartic acid to reduce amphotericin B toxivity”- “ Journal of Antimicrobial Chemotherapy” (Submitted).

 

2.                    Hasan Ahmad, A. H. M. Tarikul Islam, M. Amran Hossain, M. A. Jalil Miah, “Copolymerization of styrene with 2-hydroxyethyl methacrylate – a comprehensive kinetic study in emulsion polymerization system”-Polymer International, (Submitted).

 

^3.                      M. A. Jalil Miah, Bong K. Yoo, Eung-Seok Lee, and Kun Han, “ Synthesis of Decapeptide of L-Aspartic acid and Benzyl-L-Aspartic acid by Solid Phase Peptide Synthesis”-Arch. Pharm. Res., 28, 756-760 (2005).

4.            
                                             Ahmad,
                                             H., Miah, M. A. J. and Alam, M. A., “Preparation of Micron-sized Epoxy Functionalized Polystyrene Particles and
                                             Adsorption of Biomolecules”- J. Polym. Mater., (Accepted).

5.             H. Ahmad, M. K Mitra, M.
                                             A. B. Siddique, M. M. Rahman and M. A. J. Miah, “Radical Polymerization of styrene and methylmethacrylate in
                                             different non-aqueous dispersion media”- J. Bang. Acad. Sci., 28, 149-157 (2004).

6.            
                                             H.
                                             Ahmad, and M. A. J. Miah, “Micron–sized Monodisperse Core-shell Polystyrene/Polyaniline Composite Polymer
                                             Particle”- J. Bang. Acad. Sci., 28, 71 (2004).

7.                    Alam, S; Miah, M. A. J. and Islam, A., “Synthesis and Studies of Antimicrobial Activities of Two Benzylated Flavones”- J. Bang. Chem. Soc.,(Accepted).

8.            
                                                 Alam, M. A., Miah, M. A. J., Ahmad, H; “Micron
                                             Sized pH-Thermosensitive Composite Polymer Particles Based on 2-Dimethylaminoethyl Methacrylate and N-Isopropyl Acrylamide”- J. Polym. Mater.,  (Accepted).

9.                    Alam, S; Miah, M. A. J.; Islam, A., “Studies of Antibacterial and Antifungal Activity of Synthetic Apigenin Trimethyl Ether”- ACGC Chemical Research Communications, 18, 1 (2005).

10.                A Comparative Study of the Adsorption Behavior of Biomolecules on PMMA/P(MMA-AAm) and PS/P(MMA-AAm) Composite Polymer Particles, H. Ahmad, M. A. J. Miah, and M. A. Khatun, J. Bang. Chem. Soc., 17(2), 153 (2004).

11.                Alam, S; Miah, M. A. J.; Islam, I; “In vitro studies of Antimicrobial Activity of Synthetic Ovaliflavone”-J. Biol. Sc., 4 (4), 527 (2004).

12.                Alam, M. A., Ahmad, H.; Miah, M. A. J., “Stimuli-responsive adsorption behavior of macromolecules on PMMA/P(DM-EGDM) composite polymer particles”- J .Polym Mater., 20(3), 243-8 (2003).

13.                Alam, S; Miah, M. A. J.; Islam, I; “Synthesis and Studies of Biological Activity of Benzyl and Methyl Derivatives of 7-Hydroxyflavone”- Pakistan J Sc. Ind. Res.; (submitted).

14.                Ahmad, H.; Miah, M. A. J.; Rahman, M.M., “Preparation of micron-sized composite polymer particles containing hydrophilic 2-hydroxyethyl methacrylate and their biomedical applications” – Coll. Polym. Sci., 281, 988 (2003).

15.                H. Ahmad, Miah, M. A. J., Pervin, M.S.; Rahman, M. M.,“Composite polymer particles    prepared with different amounts of acrylic acid and their usefulness as carrier for biomolecules”- Coll. Polym. Sci., 281, 897 (2003).

16.                Mottaleb, M.A.; Miah, M.A.J.; Karim, R., “Application of Ultraviolet-Visible and Atomic Absorption Spectroscopy for Analysis of River and Pond Water samples of Rajshahi and Nawabganj Districts in Bangladesh” –Rajshahi University Studies, Rajshahi, in press.

17.                Islam, M. S.; Ali, M.M.; Miah, M.A.J.; Mandal, B.H., Ahmad, N, “Catalytic Activity of Metal (II) Glutamate Complexes on the Hydrolysis of Amino Acid Ester: A Study with Cu(II), Zn(II), Cd(II) and Hg(II) Complexes” – Jahangirnagar Univ. J. Sc.,25, 89 (2002).

18.                Rashid, M.H.; Ahmad, H.; Rahman, M.S.; Miah, M.A.J., “Production of Polystyrene/Poly (Styrene-Acryl Acetate) [PS/P (S-AA)] Composite Polymer Particles and pH-Dependent Adsorption Behavior of Macromolecules and Chloramphenicol” – J. Bang. Acad. Sci., 26(2), 127 (2002).

19.                Ahmad, H; Ali, A.M.I.; Miah, M.A.J., “Effect of Ethyl Acrylate Content in PMMA/P (MMA-EA) Core-shell Composite Polymer Particles on the adsorption behaviors of biomolecules” – J. Polym. Mater., 18, 287 (2001).

20.                Ahmad,H.; Rahman, M.S.; Miah, M.A.J.; Ali, A.M.I., “A study on the production of PMMA/P (MM-AAm) composite polymer particles and the effect of acrylamide content on the adsorption behaviors of biomolecules” – Colloid Polym. Sci., 279, 1039 (2001). 

21.                Mottaleb, M.A.; Miah, M.A.J., Karim, M.R., “Application of Chromatographic and Electrophoretic Techniques for Analysis of Biochemical-Environmental Samples” – Oriental J. Chem., 16, 211 (2000).

22.                Ahmad, N.; Miah, M.A.J.; Haque, M.R.; Ali, S.M.M., “Promotional Effect of Metal Polymer Complexes on the Hydrolysis of Amino Acid Esters: A Study with Cu (II) and Ethane Diol-Glutamic Acid Polymer Complexes” –J. Polym. Mater., 17, 283 (2000).

23.                Miah, M.A.J.,“Aldol Condensation of Cyclohexanone Catalysed By Phosphorus Oxytrichloride. Synthesis of b, g-Unsaturated Carbonyl Compound” - J. Bang.  Chem. Soc., 12, 217 (1999).

24.                Miah, M.A.J.; Chattapadhyay, S; Kalinin, A.V; Snieckus, V.,  “Anionic Homologous Fries Rearrangement of O- (2-Methylaryl) carbamates. A regiospecific Route to Benzo[b]furan-2 (3H)-ones including an Unnamed Metabolite from Helenium Species” – Synlett, 839 (1997).

25.                Miah, M.A.J.; Snieckus, V., “Directed Ortho Lithiation Methodology. Development of a New General Method for the Synthesis of 2(3H)-Benzofuranone” – J. Bang.  Chem. Soc., 8, 157 (1996).

26.                Miah, M.A.J.; Fraser, R.R., “Determination of pKa values of Carbon Acids by 13C NMR Spectroscopic Method in Tetrahydrofuran. Electronic and Steric Effects on Acidities of Carbon Acids” – Ind. J. Chem., Sec. B: Org. Chem. 35B, 71 (1996).

27.                Miah, M.A.J.; Islam, M.S.; Pal, S.C.; Barma, T.K., “Preparation and Characterization of Mixed Ligand Complexes of Co (III), Fe (III) and Cr (III) with Phthalimides and Phenols” – Pak. J. Sci. Ind. Res., 39, 106 (1996).

28.                Miah, M.A.J.; Islam, M.S.; Pal, S.C.; Barma, T.K., “Synthesis and Characterization of Mixed Ligand Complexes of Co (II) and Ni (II) Containing Imides and Phenols” – Bang.  J. Sci. Ind. Res., XXXI, 27 (1996).

29.                Miah, M.A.J.; Islam, M.S. et al.,  “Preparation and Characterization of Some Mixed Ligand Complexes of Ti (III) and Oxovanadium (IV) with Imides and Interhalogens and Cyanogen Bromides”  - J. Bang.  Chem. Soc., 8, 31 (1995).

30.                Miah, M.A.J.; Islam, M.S. et al., “Mixed Ligand Complexes of Trivalent Metal with 8-Quinolinol and Some Amino Acids” - J. Bang.  Chem. Soc., 8, 53 (1995).

31.                Miah, M.A.J.; Islam, M.S.; Pal, S.C.; Barma, T.K.,“Studies on the Complexes of Oxovanadium (IV) and Titanium (III) Containing Phthalimides and Aminophenols” – Oriental J. Chem. (India), 10, 195 (1994).

32.                Miah, M.A.J.; Saha, P.K., “Studies on Acid Catalyzed O- and N-Acylation of Phenols and Anilines” - J. Bang.  Chem. Soc., 6, 51 (1993).

33.                Islam, M.S.; Miah, M.A.J.; Roy, R.K.,  “Preparation and Characterization of Some Mixed Ligand Complexes of Chromium (III) and Titanium (III) with Succinimide and Amino Acids” - J. Bang.  Chem. Soc., 6, 131 (1993).

34.                Miah, M.A.J.; Snieckus, V., “Chemoselective Alkyl-Oxygen and Acyl-Oxygen Fission. Demethylation and Deacylation of Dihydric Phenol Derivatives” - J. Bang.  Chem. Soc., 5, 93 (1992).

35.                Ahmad, A.; Chakravarty, P.K.; Miah, A.J., “Action of Strong Alkali on Some Aromatic Nitro Compounds: Reduction and Nucleophilic substitution” - J. Bang.  Chem. Soc., 5, 179 (1992).

36.                Islam, M.S.; Roy, R.K.; Miah, M.A.J., “Mixed Ligand Complexes of Pd (II), Rh (III) and Pt (IV) Succinato with 1,10-Phenanthroline and 2,2- Bipyridine” – Synth. React. Inorg. Met.-Org. Chem. (USA), 21, 869 (1991).

37.                Miah, M.A.J.; Fraser, R.R.,“Determination of pKa values of Carbon Acids in Tetrahydrofuran by 13C NMR Technique. A Comparative Study of Acidifying Effects of Silicon and Tin on Adjacent carbon-hydrogen bond” – Ind. J. Chem., 29A, 588 (1990).

38.                Miah, M.A.J.; Fraser, R.R., “Acidity Determination of Carbon Acids by 13C NMR Spectroscopic Method in Tetrahydrofuran: Enhancement of Acidity By Ortho-Directing Group” - J. Bang.  Chem. Soc., 3, 87 (1990).

39.                Tarafder, M.T.H.; Fatema, K.; Miah, M.A.J., “Thiocyanate Complexes of Ni (II), Co (II), and Zn (II) Ions Containing Some Bidentate Neutral Auxiliary Ligands” - J. Bang.  Chem. Soc., 2, 47 (1989).

40.                Miah, M.A.J.; Fraser, R.R., “Acidity Determination of Carbon Acids by 13C NMR Spectroscopic Method in Tetrahydrofuran” - J. Bang.  Chem. Soc., 2, 77 (1989).

41.                Tarafder, M.T.H.; Miah, M.A.J.; Howlader, M.B.H.; Ahmad, A; Islam, A.A.M.A., “Synthesis of 3,5-Dimethylpyrazole-1-Benzyl dithiocarboxylate- A new Derivative of Pyrazole” - J. Bang.  Chem. Soc., 2, 73  (1989).

42.                Miah, M.A.J.; Orr, D.E., “The Synthesis of 2-Butyl-2-Tosyl-4-Butyrllactam” - J. Bang.  Chem. Soc., 1, 173 (1988).

43.                Miah, M.A.J.; Ahmad, A.; Snieckus, V., “Oxyacetylation of Phenols Catalysed by Lewis Acid” – J. Bang.  Chem. Soc.,1, 167 (1988).

44.                Miah, M.A.J.; Snieckus, V., “Directed Ortho Metalation of O-Pyridyl Carbamates. Regiospecific Entries into Polysubstituted Pyridines” - J. Org. Chem., 50, 5436 (1985).

45.                Sibi, M.P.; Miah, M.A.J.; Snieckus, V., “Ortho-Lithiated Tertiary Benzamides. Magnesium Transmetalation and Synthesis of Phthalides and Coumarins Including Mellein and Kigelin” – J. Org. Chem., 49, 737 (1984).

46.                Miah, M.A.J.; Orr, D.E., “Synthesis of 4-(1-Carbethoxyalkyl)-2-Imidazolones” – Chem. Ind., (London), 392 (1983).

47.                Tarafder, M.T.H.; Miah, M.A.J.; Bose, R.N.; Ali, M.A., “Metal Complexes of Some Schiff Bases Derived from S-Benzyldithiocarbazate” – J. Inorg. Nucl. Chem., 43, 3151 (1981).

48.                Latif, K.A.; Miah, M.A.J.,  “Synthesis of Unsymmetrical Diaroyl Sulphides”- Bangladesh J. Sci. Ind. Res., XVI, 1 (1979).

 

O. Review Article:

 

1.       M. A. J.; Hudlicky, T.; Reed, J. W., “The Cephalotaxus alkaloids” - in The Alkaloids: Chemistry and Biology;  (Cordell, G. A., Ed.; Academic Press: San Diego, USA); Vol 51, pp 199–269 (1998).

.

 

P.    Book:

 

1.      A Manuscript in Bengali of a Book entitled “Selected Organic Reactions – Mechanisms and Applications” – is in press for publication.